Cryopreservation
Uncompromising cryopreservation with Pentahibe®
Our Pentahibe® advanced cryopreservation formulas are designed to protect and preserve cells during cryopreservation. The key component of Pentahibe® is pentaisomaltose, a naturally derived alternative to dimethyl sulfoxide (DMSO).
Studies show that DMSO has a toxicity level that can induce epigenetic changes, and it can cause adverse reactions in patients such as headache, nausea, vomiting, and bradycardia. Pentahibe® is a safe and effective alternative to higher concentrations of dimethyl sulfoxide (DMSO) for the cryopreservation of cells. With Pentahibe®, you can reduce or even eliminate the use of DMSO – without compromising on safety, efficacy or functionality.
PentaHibe® is optimised for the cryopreservation of hematopoietic stem cells, mesenchymal stem cells, T cells, and tissues for organoid generation, making it an important step toward improving safety for patients worldwide.
Pentahibe® Base - in 40 mL vial
Our natural, cGMP compliant, non-toxic solution that can be used as the sole cryoprotective agent or as a base for further formulations. Pentahibe® Base (40% pentaisomaltose) offers complete flexibility and can eliminate the need for DMSO or reduce the need for DMSO to 1-2%, which significantly lowers DMSO-related toxicity and side effects.
Dextrans used in cryopreservation
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