Dextran chemistry

Dextran fractions are characterised by their average molecular weights and molecular weight distributions. Dextran is used in a wide range of industries and fields, including pharma, photography and agriculture.

Dextran is an α-1,6-glycosidic linked D-glucan with side-chains α-1,3 linked to the backbone units of the Dextran biopolymer. The degree of branching is approximately 5% in native (unfractionated) dextran and decreases with decreasing molecular weight. The branches are mostly 1-2 glucose units long.

Dextran can be obtained from fermentation of sucrose-containing media by Leuconostoc mesenteroides B512F.

Dextrans come in a wide range of molecular weights and sizes. They are soluble in water and solutions, can be filtered, have stable viscosity, and maintain a favourable osmotic environment.

Dextran fractions are stable for more than five years when stored as a dry substance (powder) in well-sealed containers at room temperature.

Dextran has been used in numerous products for human use for decades.

Dextrans have been used clinically for over 50 years, demonstrating their safety and quality.

Dextran is a biodegradable polysaccharide derived from natural sources, known for its ability to break down into non-toxic by-products. This makes it an environmentally friendly choice for various applications, including medical and laboratory use.

Carboxymethyl Dextran (CM-Dextran) in its free acid form is a white, odourless powder. While it is not a polyanion in its powder form, it acts as a polycarboxylic acid. When dissolved in neutral solutions, it becomes a polyanion, and it is freely soluble in water or electrolyte solutions.