Dextran safety

For decades, dextran has been widely used in products intended for human use, including intravenous, intramuscular, oral, and topical applications, across regions such as the United States and Europe. Its applications include plasma volume expanders, ophthalmic formulations, and oral medicinal products such as Spasfon® and Opalmon.

Dextran’s safety profile is well established through this long history of clinical and commercial use. This extensive use in regulated medicinal products is taken into account by regulatory authorities worldwide when defining toxicological, preclinical, and clinical requirements.