Pharmacosmos Amino-dextran
Amino-dextran (AmDex) is a modified form of dextran, a polysaccharide derived from glucose. By adding amino groups (—NH2), it gains new properties that expand its applications in scientific and medical fields.
Pharmacosmos Amino-dextran is based on our world-leading dextran products and produced at our state-of-the-art, GMP-approved facility in Denmark.
Versatility of amino-dextran
The key modification in amino-dextran is the introduction of amino groups, which enable it to form covalent bonds with functional groups such as carboxylic acids and aldehydes. This makes amino-dextran ideal for conjugating with biomolecules like proteins, enzymes, and antibodies, enhancing its versatility. The amino groups also allow for surface immobilization, making it suitable for biosensors and solid surface applications, such as in bioassays.
Applications of amino-dextran
Amino-dextran is widely used in drug delivery systems to control the release and targeting of therapeutic agents. In medical imaging, it serves as a component of contrast agents for MRI and fluorescence imaging. It also plays a role in nanotechnology, where it helps create nanostructures and nanoparticles for targeted drug delivery or as carriers for biological markers. Additionally, it supports cell targeting due to its biocompatibility and can modify the surfaces of medical devices to improve biocompatibility and reduce immune responses.
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