Pharmacosmos Carboxymethyl Dextran
Carboxymethyl Dextran (CM-Dextran) in its free acid form is a white, odourless powder. While it is not a polyanion in its powder form, it acts as a polycarboxylic acid. When dissolved in neutral solutions, it becomes a polyanion, and it is freely soluble in water or electrolyte solutions.
High-quality production
Pharmacosmos Carboxymethyl Dextran (CM-Dextran) is based on Pharmacosmos' world-leading dextran products and is produced at our state-of-the-art, GMP-approved facility in Denmark.
As part of Pharmacosmos' commitment to quality, CM-Dextran is developed and manufactured to the highest quality and according to the same advanced standards and requirements as applied in the development and manufacturing of our world-leading dextran products.
CM-Dextran
CM-Dextran is made by reacting dextran with Sodium Monochloroacetic Acid (SMCA) under alkaline conditions. The reaction is illustrated on the side.
CM-Dextran is a polyanion in which the content of carboxyl groups is in the range 3-20%, which corresponds to one carboxyl group for every 2.5 glucose units or less. The pKa value of the carboxyl group is approximately 4.
Contact us